Dr. Joe Cleaver

Leading Innovator in Longevity and Regenerative Medicine in Dallas County

Dr. Joe Cleaver is a physician in the fields of regenerative medicine, anti-aging therapies, and integrative healthcare. Based in Dallas, Texas, he is a board-certified rheumatologist and immunologist with over two decades of clinical and research experience. Known for his expertise in longevity and advanced therapies, Dr. Cleaver focuses on addressing the root causes of aging at the cellular level rather than merely managing symptoms.

At the forefront of personalized healthcare, Dr. Cleaver offers cutting-edge therapies tailored to the unique needs of each patient at Paradigm Wellness Medical Group LLC. His approach incorporates regenerative medicine, lifestyle interventions, and advanced diagnostics to optimize health and extend lifespan. Key areas of focus include telomere health, epigenetic age, senescent cell burden, stem cell health, and Klotho protein optimization.


An innovator in stem cell therapies, Dr. Cleaver leverages their natural healing potential to improve telomere health and reduce "inflammaging"—the chronic inflammation associated with aging. He has also established stem cell banking for longevity patients through the Cell Surgical Network™, ensuring access to this transformative therapy as part of their long-term health strategy.


As the developer of KLOTHAMAX™, Dr. Cleaver integrates a proprietary blend of ingredients to optimize Klotho protein levels, which play a pivotal role in healthspan and longevity. This therapy enhances mitochondrial function, supports telomere health, and is linked to a reduced risk of cancer and other age-related conditions. He is also advancing new Klotho-based therapies to further expand the potential of longevity medicine.


Dr. Cleaver’s contributions to regenerative aesthetics include the 4D LYFT™ Stem Cell Facelift, a groundbreaking non-surgical procedure that rejuvenates collagen, restores facial muscle health, and revitalizes skin for a youthful appearance. Utilizing ultrasound-guided placement of stem cells, this therapy exemplifies his innovative approach to integrating science with aesthetic outcomes.



A sought-after speaker and educator, Dr. Cleaver shares his expertise in regenerative medicine, senolytic science, and anti-aging strategies at national and international conferences. He also trains medical professionals and conducts clinical research, driving advancements in integrative and functional healthcare.


Dr. Cleaver is passionate about empowering patients to take charge of their well-being through lifestyle modifications, biologic therapies, and advanced diagnostics. His holistic approach redefines the boundaries of medicine, offering individuals the tools to live longer, healthier lives while improving their overall quality of life.

Dr. Cleaver's Role in Medical Advancement

longevity medicine and regenerative aesthetics specialist in Dallas, TX

Certified in Internal Medicine and Regenerative Medicine, Dr. Cleaver is globally recognized for his work in bio-identical hormone therapy, cellular health, and longevity treatments. As an educator, he lectures internationally on longevity medicine and ortho-biologic therapies.

other Professional Achievements

Inventor of the nonsurgical 4D Lyft aesthetic treatment

Faculty and teaching position at A4M and MMI

Board Certified by ABAARM in Advanced Metabolic Endocrinology with specialization in bio-identical hormone therapy

Board Certified in Internal Medicine (ABIM)

The Journey of Dr. Joe Cleaver

Charting the Path of wellness and longevity

Bridging the latest advancements in medical science with tailored wellness and longevity strategies, Dr. Cleaver's comprehensive programs are crafted to revitalize and empower individuals. His commitment to holistic care is evident in the customized treatment plans that cover a spectrum from hormonal balance to longevity, ensuring that each patient's journey is as unique as their personal health narrative. With Dr. Cleaver's guidance, clients rediscover their body's dynamic balance and innate healing potential.

WHY CHOOSE Paradigm Wellness Medical Group

Choose Paradigm Wellness Medical Group for personalized, natural treatments designed to restore your youthful vitality. Our commitment to innovative wellness and longevity solutions caters to all individuals seeking a lasting, rejuvenated appearance and improved health.

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